Soft text trials
WebFeb 16, 2024 · In 2013, two randomized trials were initiated by the International Breast Cancer Study Group: The Suppression of Ovarian Function Trial (SOFT) and the Tamoxifen and Exemestane Trial (TEXT). The results of the SOFT and TEXT trials created a paradigm shift in the management of high risk premenopausal women with estrogen receptor … WebDec 15, 2012 · Background: The SOFT and TEXT randomized phase 3 trials address two primary questions for endocrine treatment of premenopausal women with hormone …
Soft text trials
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WebOct 16, 2024 · Adjuvant endocrine therapy recommendations for premenopausal women with hormone receptor (HR)–positive breast cancer have changed on the basis of the 5 … WebDec 9, 2024 · In the three-arm SOFT trial, the 12-year DMFS rates were 87.8% with AI-OFS, 86.2% with tamoxifen-OFS, and 84.8% with tamoxifen alone. In a combined analysis of …
WebJan 12, 2024 · SOFT/TEXT SOFT: SUPPRESSION OF OVARIAN FUNCTION TRIAL TEXT: TAMOXIFEN AND EXEMESTANE TRIAL (at NYU) Both Phase III Trials; Exemestane Plus gonadotrophin- releasing hormone (GnRH) Analogue as adjuvant therapy for premenopausal women with hormone receptor positive breast cancer Goserelin (zoladex 3.6 sc monthly), … WebSOFT and TEXT are complementary trials, conducted over the same period of time and on the same patient population. Patients were randomly assigned in the following treatment …
WebMeredith M. Regan, ScD, Harvard Medical School, Boston, MA, gives an update on the 12-year follow-up results of the SOFT (NCT00066690) and TEXT (NCT00066703)... WebJan 16, 2024 · The 3-year rate of recurrence was 8.9%, and the 3-year rate of recurrence from an external control cohort from the SOFT (NCT00066690) and TEXT (NCT00066703) …
WebJul 7, 2024 · Reanalysis of BIG 1-98, SOFT, and TEXT Trials: Focus on Clinical High-Risk Subgroups. By: Celeste L. Dixon Posted: Thursday, July 7, 2024. Given recent trial results …
WebApr 7, 2024 · Peri-Implant Soft Tissue Integration in Humans: Influence of Material The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by … ird thresholdsWebJan 4, 2024 · In this study, 101 patients with advanced soft-tissue sarcoma were given 400 mg sorafenib twice daily for 28 days. Eleven patients (15%) had a partial response, and 25 patients (33%) exhibited stable disease, with median progression-free survival and overall survival of 3 and 10 months, respectively. order for a bill to become lawhttp://research.bigagainstbreastcancer.org/soft-text ird time barredWebMar 30, 2024 · Enrollment in the TEXT and SOFT trials. (A) TEXT: Between November 2003 and April 2011, TEXT enrolled 2672 patients; enrollment was suspended 1 December 2007 and re-opened by protocol amendment released in July 2008, with enrollment restarted in December 2008. ird tin numberWebFeb 15, 2024 · Abstract. Background The updated combined SOFT+TEXT analysis, after 9 years median follow-up (MFU), revealed that adjuvant E+OFS vs T+OFS significantly … ird tin registrationWebDec 9, 2024 · Trial participants were strongly recommended to resume endocrine therapy after a pregnancy attempt or success. To date, 76.3 percent have resumed their therapy, … ird tintWebMar 30, 2024 · Enrollment in the TEXT and SOFT trials. (A) TEXT: Between November 2003 and April 2011, TEXT enrolled 2672 patients; enrollment was suspended 1 December … ird to aed