WebGlypican-1 expression was found to enhance the mitogenic response of breast cancer cell lines to different heparin-binding growth factors, suggesting that up-regulation of … WebMar 29, 2024 · Glypican 6 is a putative biomarker for metastatic progression of cutaneous melanoma. Li Y, Li M, Shats I, Krahn JM, Flake GP, Umbach DM, Li X, Li LLi Y, et al. …
Glypican-1 overexpression in breast cancer OTT
WebAlignment of the glypican-6 protein sequence with all other vertebrate glypicans clearly indicates that glypican-6 is most homologous to glypican-4 (Fig. 2 and Table II). Comparison of amino acid identities between all vertebrate glypicans suggests the existence of two glypican subfamilies and possibly also subgroups within these subfamilies. Glypican-6 is a protein that in humans is encoded by the GPC6 gene. The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans. The glypicans have been implicated in the control of cell growth and division. Glypican 6 is a putative cell surface coreceptor for … See more • Glypican See more • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". … See more • GPC6 human gene location in the UCSC Genome Browser. • GPC6 human gene details in the UCSC Genome Browser. See more sainsbury\u0027s faversham kent
The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in …
WebGPC6 / Glypican 6 glypican 6. Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases (By similarity). Enhances migration and invasion of cancer cells through WNT5A signaling. WebJun 15, 2024 · Glypican 6 is a target of nuclear factor of activated T-cells, and it modulates breast cancer cell invasiveness and migration . Dinccelik-Aslana et al. found that glypican 5 and glypican 6 gene expression was significantly higher in GC tumor tissues than in a normal sample. However, the function of glypican 6 remains unclear. WebJun 26, 2024 · Glypican 6 is highly expressed in gastric adenocarcinoma and may act as a diagnostic and prognostic marker; however, the functional importance and molecular mechanism of glypican 6 in GC re … Gastric cancer (GC) is the fifth most common cancer worldwide and one of the most aggressive cancers in China. sainsbury\u0027s felix cat food