Egr2 macrophage
WebMentioning: 33 - Macrophage metabolic reprogramming during chronic lung disease - Ogger, Patricia P., Byrne, Adam J. WebFeb 11, 2024 · Perivascular macrophages, which are resident brain macrophages, originate from the same pool of yolk sac hematopoietic progenitors, migrate to the brain early in development, ... (EGR1 and EGR2).
Egr2 macrophage
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WebATF3 and EGR2 gene expression levels in sdLDL-treated macrophages of patients with coronary artery stenosis Background: The metabolism of cholesteryl esters (CEs) is under the control of a gene network in macrophages. Several genes such as ATF3 and EGR2 are related to cholesterol metabolism. WebEGR2 (also termed Krox20) is a transcription regulatory factor, containing three zinc finger DNA-binding sites, and is highly expressed in a population of migrating neural crest cells. …
WebEGR2 is a zinc finger transcription factor which binds regulatory domains of target genes, including those critical for myelin formation and maintenance such as MPZ, PMP22, GJB1, and PRX. 66–68 Most mutations lie in the zinc finger domains, likely affecting DNA binding and transcription of these genes.69. View chapter Purchase book. WebOct 1, 2024 · The most significantly highly expressed TFs in M1 and M2 macrophages were identified by RNA-seq as Irf1 and Egr1, with LogFC values of 3.2 and 2.8, …
http://genesdev.cshlp.org/content/34/21-22/1407.full WebNov 1, 2024 · EGR2 is a direct target of IL-4-activated STAT6, having broad action indispensable for 77% of the induced gene signature of alternative polarization, …
WebMacrophage polarization to the M1-like phenotype after infection with E. faecalis was evident by the lower expression of EGR2; marker for M2 macrophages. A. Flow cytometry scattergrams showing the percentage % expressions of EGR2. B. Bar chart showing the mean percentage of F4/80-positive cell populations in the control and experimental …
WebApr 2, 2009 · Two cytokines, macrophage colony-stimulating factor (M-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to promote differentiation of monocytes into macrophages with distinct phenotypes existing in vivo. It is known that M-CSF differentiated macrophages are very similar to peritoneal … correcting a pull in golfWebJul 10, 2024 · Macrophage mRNA gene expression was determined using Taqman quantitative Real-Time PCR on cDNA templates. cDNA was generated from 500 ng RNA/sample using oligo (dT) 12–18 primers and Superscript III (Life Technologies), according to the manufacturer’s instructions. fareham swimming clubWebMay 6, 2024 · Mechanistically, we show that EGR2 is driven by TGF-β and CSF-2 in a PPAR-γ-dependent manner to control alveolar macrophage differentiation. Functionally, … fareham thai massageWebAlveolar macrophages meet various types of particulate substances deposited deep in the lung. We report differences in biologic responses of alveolar macrophages between … correcting application data sheetWebSep 27, 2024 · Of note, lung macrophages also display higher expression of proresolution M2 markers CD206 and EGR2 than peritoneal macrophages, a phenotype that is independent of calponin 2 . This indicates that calponin 2 may contribute to inflammation by promoting M1-like polarization of macrophages and not by limiting M2-like polarization. … correcting a sentence onlineWebEGR2; IL-4; macrophage polarization; epigenomic regulation; transcription factor network; Macrophages are innate immune cells that are highly heterogenous and plastic, able to … fareham thalesWebNov 19, 2024 · EGR2 fulfills lung macrophage potential. Alveolar macrophages are important for maintaining lung homeostasis and protecting the lungs against injury and … correcting asic records