Webmg/mL of propofol suitable for intravenous administration. Propofol is chemically described as 2,6-diisopropylphenol. The structural formula is: Propofol is slightly soluble in water and, thus, is formulated in a white, oil-in-water emulsion. The pKa is 11. The octanol/water partition coeff icient for propofol is 6761:1 at a pH of 6 to 8.5. WebDec 16, 2015 · The authors concluded that propofol has the potential to cause life-threatening hypersensitivity reactions in patients with allergies to egg and/or soybeans. Thus, with somewhat speculative evidence, allergy to egg, peanut and soy had been causally-associated with propofol allergy. The connection with peanut allergy arose …
Fact Sheet 12 - Food and Drug Administration
WebPropofol is unique among parenteral anesthetics in that it is known to affect mitochondrial metabolism by at least 4 sepa-rate mechanisms. In vitro, propofol has been shown to uncou-ple oxidative phosphorylation and inhibit complexes I, II, and IV.25,37,38 The strongest effect of propofol is that it inhibits the Webdichtheid. De verdeling van iets per oppervlakte-eenheid, bijvoorbeeld de maat van de massa van een stof per volume-eenheid of de hoeveelheid wooneenheden per km2 … small bumpy rash on arm
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WebApr 1, 2024 · increased watering of the mouth. irritability. joint pain or swelling. loss of appetite. mood or mental changes. muscle aches, cramps, or pains. muscle spasms or … WebAug 4, 2012 · Propofol is a milky white fluid used in anesthesia. Its color and effect have led to its nickname, "milk of amnesia." The levels of anesthesia can be thought of as a continuum from conscious, awake … WebUsing Precedex + propofol at the same time for a little while in order to transition to just Precedex makes sense. Or using Precedex for an SBT and then switching back to propofol if needed or having the option to continue on just Precedex also makes sense. What doesn’t make sense is to continuously be on both. small bumpy rash on stomach