WebSep 6, 2024 · (a) Schematic illustration to show formation of a hydrogel through click chemistry. (b) Gelation time of the hyaluronic acid/chondroitin sulfate (HA/CS)/gelatin click hydrogel as a function of CuCl concentration. (c) Macroscopic and (d) microscopic images of the hydrogel taken with a digital camera and by cryo-SEM at −195°C, respectively. WebSep 22, 2024 · All click-hydrogels exhibited a similar degradation profile that was comparable with hydrogels synthesized in PBS, which demonstrates that the thiol–yne click chemistry is highly adaptable, forming virtually the same PEG network regardless of the solvent polarity or catalyst used. Therefore, the control over the stereochemistry …
Click Chemistry Hydrogels for Extrusion Bioprinting: …
WebTechnologies. Pascal is a development-stage medical technology company that produces advanced synthetic polymer products used to make orthopedic, spine and neurosurgery safer and more effective. We are developing safe and effective synthetic polymeric CLICK-polyethyelene glycol (PEG) hydrogel to seal surgical and traumatic leaks, and release ... WebJun 1, 2014 · The click hydrogels, and in particular the in situ forming hydrogels, have demonstrated a great potential as functional extracellular matrices for tissue engineering … christoph gerber publica
Institute of Physics
WebSince “click” chemistry was first reported in 2001, it has remained a popular research topic in the field of chemistry due to its high yield without byproducts, fast reaction rate, simple reaction, and biocompatibility. It … WebJun 1, 2014 · Pseudo-click hydrogels. Pseudo-click chemistry including thiol-Michael reaction and aldehyde-hydrazide coupling reaction has also been broadly employed for … WebNov 14, 2024 · Herein, chitosan-based interpenetrating network (IPN) hydrogel was prepared in one pot via amino-maleimide click reaction and photopolymerization. First, polyethylene glycol (PEG) was modified with maleimide propionic acid (MI) to obtain functionalized polyethylene glycol (PEG-MI). Second, a transparent aqueous solution of … christoph gebald climeworks